The Institute of Science ( Formerly known as Royal Institute of Science (RIS)) is an institution of postgraduate education and research located in Mumbai, India. It is managed by the Government of Maharashtra and is currently affiliated to the University of Mumbai. Established in 1920. its research centers around all branches of science including Physics, Chemistry, Biology, Microbiology, Mathematics, Biochemistry, Bio-Technology and Environmental studies. In Maharashtra state and University of Mumbai, some programs like Masters in biochemistry were available only in the Institute of Science until recently. It offers M.Sc and Ph.D. programs and currently it does not offer undergraduate programs. Though The Institute offers M.Sc and Ph.D programs of the University of Mumbai, due to the autonomy granted to the institute, the admissions to these programs are managed separately by The Institute but examinations are conducted by the University of mumbai and degrees are awarded by the university of Mumbai. 'The Institute of Science, Mumbai' was founded by Baron Sydenham. The Institute's buildings were constructed using funds from private donations.