Sanford USD Medical Center is a hospital in Sioux Falls, South Dakota, USA. It is operated by Sanford Health. With nearly 500 beds, Sanford University of South Dakota Medical Center is the second largest tertiary hospital in South Dakota behind Avera McKennan Hospital, serving as one the primary teaching institutions for the Sanford School of Medicine, University of South Dakota. Employing nearly 4,500 staff, Sanford USD Medical Center is the largest employer in Sioux Falls. As a full-service community-owned hospital, Sanford provides a full complement of medical and surgical care, both inpatient and outpatient, in all specialties with Centers of Excellence for: As part of an integrated health care system, Sanford USD Medical Center serves as a regional medical center, with half of its patients coming from outside the immediate Sioux Falls community. Tertiary-level specialty services connect Sanford USD Medical Center with other health-care facilities and physicians in communities throughout the region. As a community-owned health care organization, Sanford USD Medical Center plays a leadership role in the development of new health services for the community.