The Technion – Israel Institute of Technology (Hebrew: הטכניון – מכון טכנולוגי לישראל‎) is an institute of technology in Haifa, Israel. Originally called the Technikum, it was founded in 1912. The emphasis was on natural sciences, engineering and architecture, with a school of medicine added later. The Technion is home to Israel's first Nobel laureates in science, Avram Hershko and Aaron Ciechanover who won the 2004 Nobel Prize in Chemistry for discovering the ubiquitin system — the mechanism responsible for disassembling protein in the cell. In 2010, the Technion's Computer Science Department was ranked fifteenth in the world. Likewise, the Technion's Faculty of Electrical Engineering has been ranked among the top fifteen electrical engineering departments in the world. Its engineering/technology and computer sciences faculties have been ranked among the top sixty in the world. In the 2010 QS World University Rankings it ranked 44th in Natural Sciences and 57th in Engineering & IT, while it came 235th in Life Sciences & Biomedicine. Its overall global ranking was 159th.