The Sapienza University of Rome, officially Sapienza – Università di Roma, formerly known as Università degli studi di Roma "La Sapienza", is a coeducational, autonomous state university in Rome, Italy. It is the largest European university and the oldest of Rome's three state-funded universities; Sapienza was founded in 1303, more than six centuries before Tor Vergata and Roma Tre. In Italian, sapienza means "wisdom" or "knowledge". According to the Academic Ranking of World Universities published by the Institute of Higher Education of Shanghai Jiao Tong University, Sapienza University of Rome ranks among the top 30 European universities. In 2010 QS World University Rankings ranked the university 190th overall in the world. Sapienza University of Rome was founded as La Sapienza in 1303 with the bull In supremae praeminentia dignitatis issued on 20 April 1303 by Pope Boniface VIII, as a Studium for ecclesiastical studies more under his control than the universities of Bologna and Padua.