The Royal University of Santiago de Compostela - USC (Galician: Real Universidade de Santiago de Compostela - USC, Spanish: Real Universidad de Santiago de Compostela - USC) is a public university located in the city of Santiago de Compostela, Galicia, Spain. A second campus is located in Lugo, Galicia. The university traces its roots back to 1495, when a school was opened in Santiago. In 1504, Pope Julius II approved the foundation of a university in Santiago but "the bull for its creation was not granted by Clement VII until 1526". In 1555 the institute began to separate itself from strictly religious instruction with the help of Cardinal Juan Álvarez de Toledo and started to work towards developing other academic fields, including the emerging science fields. Today the university's facilities cover more than 1,300,000 square meters (~320 acres). In terms of human resources, the university has more than 2,000 teachers involved in study and research, over 42,000 students, and more than 1,000 people working in administration and services.