The Pontifical and Royal University of Santo Tomas, The Catholic University of the Philippines (colloquially UST or "Ustê". Filipino: Unibersidad ng Santo Tomas), is a private Roman Catholic university run by the Order of Preachers in Manila. Founded on April 28, 1611 by archbishop of Manila Miguel de Benavides, it has the oldest extant university charter in the Philippines and in Asia. and is one of the world's largest Catholic universities in terms of enrollment found on one campus. UST is also the largest university in the city of Manila. As a Pontifical University in Asia, UST is the only university to have been visited by two popes three times: once by Pope Paul VI on Nov. 28, 1970, and twice by Pope John Paul II on Feb. 18, 1981 and January 13, 1995. The University is composed of several autonomous faculties, colleges, schools and institutes, each conferring undergraduate, graduate and postgraduate degrees, and the basic education units. Several degrees have been accredited by the Commission on Higher Education as Centers of Excellence and Centers of Development. The Patron of the University is St. Thomas Aquinas, while St. Catherine of Alexandria is the Patroness.